Best answer I can find so far. This affects many men as they age and extends up to the knee and sometimes beyond. Thought to be a lower level of testosterone but it appears that ...It’s not the lower level of testosterone per se that causes the hair loss. Testosterone is broken down by an enzyme, 5-alpha reductase, to form dihydrotestosterone (DHT). It is an excess of DHT that actually causes the hair loss, not the deficiency of testosterone.
Progesterone acts as an inhibitor of 5-alpha reductase, but older men experience a reduction in progesterone levels. This in turn cause increased 5-alpha reductase activity, which causes in increase in DHT, which shuts down follicles. Whew!
Progesterone acts as an inhibitor of 5-alpha reductase, but older men experience a reduction in progesterone levels. This in turn cause increased 5-alpha reductase activity, which causes in increase in DHT, which shuts down follicles. Whew!