What Is The Difference Between Phenylephrine HCL And Pseudoephedrine Hydrochloride?

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Anonymous Profile
Anonymous answered
Phenylephrine is α1-adrenergic receptor agonist and is used in decongestant in cough syrups, in eye drops to dilate pupil and in as vasopressor to increase blood pressure in some patients with hypotension.  Phenylephrine does not cause the release of endogenous noradrenaline, so side effects like  insomnia, anxiety, CNS stimulation, irritability and restlessness are less likely to occur.
Pseudoephedrine is a sympathomimetic amine and also use as decongestant. Pseudoephedrine causes the release of endogenous noradrenaline, so side effects like insomnia, anxiety, CNS stimulation, irritability and restlessness are  likely to occur.
Pseudoephedrine is being replaced by Phenylephrine due to its popularity as a precursor in the illicit synthesis of methamphetamine.
Penny Kay Profile
Penny Kay answered
At this point since I am not a pharmacologist, I can tell you that one is being controlled and the other is not. They both work to ease symptoms of allergy and cold, however pseudo ephedrine is used in the production of methamphetamine, and because of that, it is being controlled.

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