Temazepam trade name Restoril, among others is a short to intermediate acting 3-hydroxy benzodiazepine derivative. It is a powerful hypnotic drug generally prescribed for the short-term treatment of severe insomnia in patients who have difficulty falling asleep and maintaining sleep and where other treatments have failed. Therapeutic and supratherapeutic doses of the drug can manifest clinical effects of strong hypnosis, sedation, amnesia, and ataxia. In addition to its strong hypnotic activity, temazepam has powerful amnesic, anticonvulsant, anxiolytic, sedative, and skeletal muscle relaxant properties.
Temazepam is officially indicated for severe or debilitating insomnia and other severe or disabling sleep disorders. Temazepam is a hypnotic agent. The prescribing guidelines in the UK limit the prescribing of hypnotics to two-to-four weeks due to concerns of tolerance and dependence. In sleep laboratory studies, temazepam significantly decreased the number of nightly awakenings but has the drawback of distorting the normal sleep pattern. The United States Air Force uses temazepam as one of the hypnotics approved as "no-go pills" to help aviators and special duty personnel sleep in support of mission readiness. "Ground tests" are required prior to authorization being issued to use the medication in an operational situation.
In addition to treating insomnia, temazepam is also used as a pre-anaesthetic in surgery. A study conducted on adult women undergoing minor gynaecological surgery in a dose of 30 mg and compared to 10 mg of diazepam. The sedative effect of temazepam was found to be profoundly superior to that of diazepam, using both objective and subjective criteria for assessment. There was also a highly significant degree of patient acceptance of the drug. It is suggested that temazepam is a suitable drug for premedication for minor surgery.
The half-life, of temazepam is the amount of time it takes to get the drug down to 50% or less in your body can vary from 8 to 20 hours, which means if you have taken it several times, a high dose, or are taking it on a regular basis, then you are looking at several days, perhaps even a week, before it clears out of your system.
Temazepam is officially indicated for severe or debilitating insomnia and other severe or disabling sleep disorders. Temazepam is a hypnotic agent. The prescribing guidelines in the UK limit the prescribing of hypnotics to two-to-four weeks due to concerns of tolerance and dependence. In sleep laboratory studies, temazepam significantly decreased the number of nightly awakenings but has the drawback of distorting the normal sleep pattern. The United States Air Force uses temazepam as one of the hypnotics approved as "no-go pills" to help aviators and special duty personnel sleep in support of mission readiness. "Ground tests" are required prior to authorization being issued to use the medication in an operational situation.
In addition to treating insomnia, temazepam is also used as a pre-anaesthetic in surgery. A study conducted on adult women undergoing minor gynaecological surgery in a dose of 30 mg and compared to 10 mg of diazepam. The sedative effect of temazepam was found to be profoundly superior to that of diazepam, using both objective and subjective criteria for assessment. There was also a highly significant degree of patient acceptance of the drug. It is suggested that temazepam is a suitable drug for premedication for minor surgery.
The half-life, of temazepam is the amount of time it takes to get the drug down to 50% or less in your body can vary from 8 to 20 hours, which means if you have taken it several times, a high dose, or are taking it on a regular basis, then you are looking at several days, perhaps even a week, before it clears out of your system.
