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How Does Naloxone Prevent I.v. Us Of Suboxone?

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Anonymous Profile
Anonymous answered
I can tell you from personal experience that if you are stabilized on Suboxone and you do it intravenously you will not get sick. I have done it many many times to make my subs last longer. When I do the suboxone through IV I only have to do very small pieces because the bio availability is basically 100%. The Bio availability of Suboxone sublingually(under the tongue) is only 33% which means if you put a 8mg tablet under your tongue your body is only going to process a third of it and the rest is just wasted. Snorting is a much more healthy solution and brings the bio-avail. Up to 70%.

From what I can tell the naloxone does nothing to prevent you from IV'ng the drug, because I have personally done it many many times. My personal opinion is they put the 2mg of naloxone in the drug to get it to pass FDA approval easier.

But let me be clear, IV suboxone is not healthy, I shouldnt do it but I have to make my prescription stretch until I see the doctor again. I have a wheel filter I use for suboxone and I filter it twice. One thing I have noticed that is bad from IV suboxone is it makes the vein hard, and it will take a few days for it to go back to normal. Snorting and IV is also the only way I have ever got a buzz from suboxone and got a "nod". Also I have never shot a whole 8mg pill at once, 4mg is the most I have ever done in one shot and normally I only put a sixteenth
(half of a milligram) of a pill in the spoon to prepare for IV.
Anonymous Profile
Anonymous answered
If it makes your vein hard, that means you are doing it wrong.  That means you missed your vein, stupid.  I IV suboxone plenty of times and I can say my vein didn't get hard.
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Anonymous answered
Someone who shoots IV suboxone calling another person stupid. Classic.
Michelle Henning Profile
Suboxone is an approved treatment for opiate dependence and pain relief. Suboxone is a combination of two medications, buprenorphine and naloxone. Buprenorphine reduces withdrawal symptoms and blocks the effects of subequent administered opiods to help reduce illicit opiod use. Because suboxone contains naloxone in it, it can produce severe withdrawal symptoms if misused intravenously. When used as prescribed, no such effect occurs (orally).
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Anonymous answered
It doesnt "prevent" it, you just wont get high. For example you take 8mg of sub. Then decide you want to shoot heroin an hour later, your not going to feel the heroin. Its a waste, the naloxone blocks the opiates.
thanked the writer.
Anonymous
Anonymous commented
Actually, buprenorphine's affinity to the receptors in the brain is amazingly high and therefore "PREVENTS" you from getting high on most any other opioid, no matter how much is taken. The Naloxone in the Suboxone pill is there to discourage people from shooting it, with the idea that the Naloxone will throw you into immediate w/d when used via IV. Also, an hour after taking bupe, the naloxone is out of your system. Swim IV's Suboxone often with no ill effects, figure that one out =)

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