Yes, but ONLY if you are taking only suboxone. If you are on other kinds of opiates like; oxycodone, hydrocodone, morphine, hydromorphone, oxymorphone, heroin, or any others there is a chance you will go into severe withdrawal, trust me! Not fun. I was slamming 600mg of oxycodone daily for months and I ran out so I waited 48 hours before doing any more opiates.Thinking that all the oxycodone was completely out of my system, then I shot up some suboxone(half of a 2mg suboxone)and and it put me into severe withdrawal. It was without a doubt the worst time I ever went thru withdrawal and ive been taking opiates for over 6 years now. I had no choice but to make some phone calls and find some oxys to get me back to normal, so if you only have suboxone in your system then give it a try but be careful. Try half of a 2mg first. Make sure you dissolve it completely.